Hiko on 15 March 2009
I never played any Metal Gear Solid games before I played Metal Gear Solid 4 on PS3.
I can tell you that you don't have to play any previous Metal Gear Solid games to enjoy MGS4.
In fact, MGS4 is one of my favorite games I played in the past 3-4 years.
I played it fully the first time (watching all the cut-scenes). Then I finished it at least another 3-4 times.
On top of that, they included Metal Gear Solid Online which is very fun.
I would highly recommand you to buy this game. I'm sure you can get it for a very good price now.
Also, there's a Free DLC of a Metal Gear Solid Database that explains many things from the previous games and the current one.
At some point, something must have come from nothing...
...nothing can come from nothing...
