Check that, Kwaad. Try a keyboard along with a flight stick.
i'm not going to manage a space station with just a flight stick. Who does?
The RTS is a perfect example of a complex game with not very many buttons. It traditionally hasn't transferred very well because there is yet to be a device that is as dextrous as a mouse. Actual gameplay itself can be done with one or two clicks of the mouse.
and I don't understand what you're trying to get at with the mouse - two button controller analogy. The mouse is analogous (sp?) to what the Wii does. Instead of using a keyboard to play a game like Chess or even any FPS, the mouse has replaced a whole bunch of functions of the keyboard- making a game "simpler" yet more "complex" at the same time.