Left 4 Dead Space.
I like to mash the names together and then consider what kind of game with this new name would be like, so I don't have to answer the original question. Consider this definition of dead space:
http://dictionary.reference.com/browse/dead%20space
I would consider it to be a simulation of a sort involving performing triage during a war. And unlike the other two games, it would be first designed for the Wii, and use the Wii remote wave feature excessively.