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The differences are negligible and people who only have a PS3 shouldn't feel slighted.

I was kind of disappointed in the Demo, the game looked great, but the gameplay seemed a little off. I was a huge fan of RE4, but this left me underwhelmed in some respects.

However, I'm still going to buy this game because of the Offline/Online Co-Op which will be a ton of fun. I'll probably get it for PS3 because most of my friends who are gonna get RE5 have a PS3.