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@ kyliedog: You have to be able to switch your mindset to the game. The setting is aliens and spaceships. Everything else (aside from the increased capabilities gained from the mutation with those genes) is what we know and are capable of in the real world.

Therefore, picking up a shotgun, a machinegun, a LAARK, a pistol, 17 grenades and 700 clips of ammo is a bit much.

Other games don't hinge on this factor and that's just fine, but being restricted (as one should expect) is not a troublesome factor in this game.