As Dogs Rule already made an excellent of all possible choices, I'll post some of my most favourite 80s songs instead (one song per artist/band only; tough choice, as I could list 5 to 10 brilliant 80s songs from single artists/Bands - such as Prince, Stevie Wonder, Kate Bush, Prefab Sprout or The Smiths):
ABC/The Look of Love
Anita Baker/Sweet Love
Blondie/Call Me
The Boomtown Rats/I Don't Like Mondays
David Bowie/Ashes To Ashes
Kate Bush/Running Up That Hill
The Church/Under the Milky Way
The Clash/Rock the Casbah
Culture Club/Do You Really Want To Hurt Me
The Cure/Close To Me
De La Soul/Me, Myself and I
Depeche Mode/Enjoy The Silence
Devo/Whip It
Dexys Midnight Runners/Come On Eileen
Echo & The Bunnymen/The Killing Moon
Eurythmics/Sweet Dreams (Are Made of This)
Donald Fagen/I.G.Y.
Dan Fogelberg/Same Old Lang Syne
Peter Gabriel/Games Without Frontiers
Marvin Gaye/Sexual Healing
Heaven 17/Let Me Go
Don Henley/Boys of Summer
Bruce Hornsby & the Range/The Way It Is
Human League/Don't You Want Me
The Jacksons/Can You Feel It?
Janet Jackson/Rhythm Nation
Joe Jackson/Steppin' Out
The Jam/Town Called Malice
Billy Joel/Allentown
Joy Division/Love Will Tear Us Apart
K.C. & The Sunshine Band/Don't Go
Chaka Khan/I Feel For You
Kid Creole & the Coconuts/Stool Pigeon
Kinks/Come Dancing
Knack/My Sharona
Cyndi Lauper/Girls Just Want to Have Fun
Living Colour/Cult of Personality
Madness/Our House
Men Without Hats/Safety Dance
Van Morrison/Wild Honey
New Order/Blue Monday
Randy Newman/I Love L.A.
Olivia Newton-John/Physical
Stevie Nicks with Tom Petty & The Heartbreakers/Stop Draggin' My Heart Around
Pet Shop Boys/West End Girls
The Pixies/Monkey Gone To Heaven
The Pointer Sisters/I'm So Excited
The Police/Every Little Thing She Does Is Magic
Prefab Sprout/When Love Breaks Down
Pretenders/Brass in Pocket (I'm Special)
Prince/Let's Go Crazy
Public Enemy/Fight the Power
R.E.M./It's the End of the World as We Know It (And I Feel Fine)
Sade/Smooth Operator
Bob Seger & the Silver Bullet Band/Against the Wind
Paul Simon/You Can Call Me Al
The Smiths/How Soon Is Now?
The S.O.S. Band/Your Time (Do It Right)
Soft Cell/Tainted Love
Bruce Springsteen/I'm On Fire
Steely Dan/Hey Nineteen
Supertramp/Take the Long Way Home
The Stranglers/Always The Sun
The Style Council/Walls Come Tumbling Down
Talking Heads/Once In A Lifetime
The The/Uncertain Smile
Thompson Twins/Love On Your Side
Tina Turner/Private Dancer
U2/Where the Streets Have No Name
Suzanne Vega/Luka
Violent Femmes/Blister in the Sun
Visage/Fade To Grey
Wang Chung/Dance Hall Days
Steve Winwood/While You See a Chance
Womack & Womack/Teardrops
Stevie Wonder/That Girl
XTC/Senses Working Overtime
Yarbrough & Peoples/Don't Stop The Music
Neil Young/Rockin' In The Free World
IMO Prince was the best and most important new artist of the 80s (although his career already started in the late 70s), so if had to chose one song my vote would go to Let's Go Crazy.
