The biggest issue with the Prime series is that it does try to take expectations and reverse them. That's not how intuitive games work, and is actually why Prime 3 has a bit of a counter-response to the problem by having more enemies to fight and more one-on-many brawls. Intuitive games take your expectations and run with them; if they're especially good, they take those expectations to new levels. But Metroid cannot do that with first-person perspective and expect to succeed. The concept is just close enough to that of an FPS to be incompatible. Hence why I say a 2D entry is the best bet. Or a third-person 3D entry, possibly...
Sky Render - Sanity is for the weak.