1. (Wii) Next Zelda
2. (Wii)Monster Hunter 3
3. (Wii)Dragon Quest X
4. (360/PS3)Resident Evil 5
5. (360/PS3)Street Fighter 4
Also I would love a new Mariogame but I´m not so sure we´ll see one more this generation. A new Kid Icarus would soar to the top of my list but that isn´t confirmed yet is it?
My biggest wish would be a new games of these in either 2d or 3d with a fixed camera (like Super Mario Galaxy):
Pokemon rpg Wii
Castlevania Wii
Metroid Wii (this would be the best thing that could ever happen!)