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Go to http://www.download.com. Download and install two programs:

Security Task Manager 1.7g and Unlocker 1.8.7

Run Security Task Manager first. It will catagorize all running files by a threat rating. Google any files before removing them to make sure the file is actually a virus, not a vital system process. To remove a file, select it, click remove, select the 'Move File to Quarantine' option and UNCHECK 'Create Restore Point'

This should get rid of most items. Anything else that you can't get rid of, make a note of the location.

Install Unlocker (make sure to uncheck the options you don't want to install, like eBay toolbar). Find the files that couldn't be removed earlier, right click them, and select Unlocker. Choose the Delete option from the dropdown menu and select Unlock. You may get a bluescreen after the file is forcefully deleted, just turn your computer off and back on if you do. This works for me in most cases, screw antivirus and scanning tools. They don't work very well.