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Get Scrounger perk you will hardly ever run out of bullets (plus have extra to sell for the one you don't need or used).

Small guns are easy to come by especially early and they remain good throughout the games.

As for big guns, I have tons of ammo for Minigun but I don't really like it as it's very inaccurate and slow to start. I do like missile though just for area blast.

My favorite weapon however is the unique Uzi and Riley's combat armor. I put tons of perks for small gun and AP bonus and I always have enough AP to keep staying in VAT with the Grim Reaper perk at the end.