If you like online gaming with friends more go R2. If you like action adventure with great storytelling more then get Uncharted.
My vote would be Uncharted because its one of my favorite PS3 games next to MGS4.
Uncharted took me around 10 hours my first time through. And I played through it 4 times. The fourth time was for trophies on impossible difficulty. The other 3 times was before the trophy patch. Love that game!
Resistance 2 single player story was pretty fun & it took me around 10 hours. Obviously with online multi-player your time with this game could blow past Uncharted. Unfortunately, I didn't really get into the multi-player because I didn't find it that much fun. You can only be a soldier, spec ops, or medic and the online enemy AI on the bosses is very weak. They just stand there doing nothing sometimes. Some people absolutely love it though, but if you played the beta then you know exactly what its like.
