Here are the issues I have with PC games at the moment.
1. Production values: Patches, frame-rate stability (What do you mean im suddenly texture limited?!) and they don't always work. For example Even L4D was a bitch to get working because the virus scanner quarentined the exe file.
2. Complex/elitist gameplay on a lot of games. Strategy games have gotten so complex that halfway into it I feel like throwing up my arms and saying "WTF is going on?!?!" With shooters, because the mouse is so accurate all the time it feels wrong to be able to pull off a headshot ~95% of the time and that means im aiming at floating heads, ignore the body. Seriously, why can't I miss? I personally hate the headshot or else mantra, and I hate having a crosshair all the damn time when shooting from the hip and I hate the accuracy of the mouse.
3. Computer monitors are inefficient games platforms. You may think that its nice to have a 30" 2560/1600 Dell monitor, but wait till you see the graphics card you have to run it with. Theres a reason why consoles can get away with a 128bit bus and PC graphics cards need up to 4x the bandwidth. 4870 1gb is the minimum entry point at $299 for such a monitor.
4. Piracy, its not about not having games. I hate knowing that for every copy I bought there are 5-10 people who are playing without paying. I don't even go to a retail store anymore... if its not on Steam or Good old games im not buying it.
5. Resale/rental. I know there are some games i'll play only once so I get to play a lot more one off experiences because I know its easy to dispose of the game afterwards if I know im not going to play it again.
6. Controller vs Keyboard > Mouse vs stick for me. Added bonus is force feedback, absolutely love it! It gives me that tactile response that I miss from the mouse. Also it doesn't feel like im playing a balarina on speed with the ability to shoot more accurately on the move than someone with a steady aim at a firing range.
They are my main gripes. 
Tease.
