Of course, the big assumption that I make is that Gran Tourismo 5 will not be released in 09. Even if FFXIII will be released in 09, its PS3 sales will be diluted by the sales of the 360 version, and Japanese sales won't make much of a difference.
Here's how the God of War series has done so far:
God of War:
0.02 million in Japan
2.48 million in America
0.71 million in Others
Total: 3.21 million
God of War 2:
0.04 million in Japan
1.6 million in America
0.67 million in Others
Total: 2.31 million
God of War Chains of Olympus:
0.04 million in Japan
0.91 million in America
0.33 million in Others
Total: 1.28 million.
I simply don't see any other title that's high profile enough to beat God of War III.
Currently playing on PS3: God of War III
Currently playing on Xbox360: Final Fantasy XIII
Currently playing on NDS: Chrono Trigger