I won't be buying Fallout 3.
I'm one of the few people that find bethesda to be an overhyped developer and that their games are clunky in design.
You can call me a noob or whatever, but if the games controls aren't intuitive enough on the default setting that I can make my way through the games first dungeon/area without dying continually, there's something seriously wrong with the game design.
Fallout 3 looks like a game with a compelling story but lacking in the controls/gameplay department (much like mass effect, except I love bioware).
Also, the two versions available to me (PS3 or PC) have serious issue with them, I'm definitely not paying for a lazy port or spyware (if the reports are to be believed).