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I actually think it would be between Gears 2 and Animal Crossing. THe reason why Animal Crossing sold better on the DS is because of the 1 Larger Userbase than the GC, and there being a greater number of "Casual" players on the DS than GC. So it should do just as good or better on the Wii. Also Nintendo seems to pushing it alot more than the DS version and Wii Speak being bundled with it optionally that might boost demand as well. Also wasn't the GC version only a port of the N64 version? Meaning a good number of people probably didn't buy it for that reason. Resistance 2 will sell good as well and a considerable amount more than the first, just not as good as Gears 2 or Animal Crossing imo. I do think R2 will be the best game out of the 3 though.