Yep with 4 millions shipped they conservatively made around 100 millions $ so far, more is Sony picked up the marketing tab ( which they probably did).
With that amount of revenue I think it's conservative to think they have already made 40% ROI on the game ( development costs would have to be over 74 million $ for it not to be the case and I doubt they were that high).
If you ballpark the development costs at 50 million $ ( which seem more reasonnable) you get a 100% ROI so far with still more sales to come...
Seems like a good investment for me...
As for number 1 franchises, I would actually expect PES to be the number 1 revenue maker for Konami. It has a yearly released that sells over 1 million units and additional costs on new versions are minimal aside from licencing costs with soccer clubs...