Not possible this generation.
When company enjoys success for few years they tend to end in "We are invincible and consumer will love us whatever we do" mode.
Not necessarily. Nintendo's aware of the 3DS' slow start, for one, and Iwata acknowledged that it was a mistake, so likely one they'll rectify for Wii U (by actually having a killer app at or much closer to launch)
Monster Hunter: pissing me off since 2010.