From the stuff I saw, in my DEF buy list are

1. GT

2. TM

3. MOH: (especially with frontline)

4. DEAD SPACE

5. Sorcery (best new IP shown the whole show if not maybe the best game demo also)

6. KZ3

7. Infamous

8. Kid Icarus

9. Vanquish

10. Heroes (R&C and JAK in one game? with SLy to boot? HELL YEAH)

cant wait for them to come out

Weren't a lot of games I really saw that WOW'd me this year, but I'll definitely be getting LBP2, AC: Brotherhood, Twisted Metal, and a big maybe for GT5 (not a big racing fan, but who didn't have that demo on first gen PS3s?).

Not a shooter fan or a Nintendo fan, so this year with all the motion control and 3D sort of let me down. I'll be more interested to see what in-house announcements are made in the coming weeks/months.

Man, so many:

Paper Mario 3DS

Kirby's Epic Yarn

Donkey Kong Country

The Legend of Zelda and the Skyward Sword

Mariokart 3DS

Goldeneye

Kid Icurus

Epic Mickey

Metroid: Other M

Rage

Bulletstorm

Joy Ride

Kinect Sports

Dance Central

Your Shape

Fable 3

Gears of War 3

Twisted Metal

Little Big Planet 2

It's hard to gauge if I'm more excited about the Nintendo or MS games, probably the Nintendo games but I really want to play the Kinect games.  I've looked at the games announced at the Sony conference and they range from don't interest me (Killzone 3, GT5, inFamous 2, ect), I don't want 3D with glasses, and at the moment I have no desire to spend $150 on a Move.

Definitely for Wii:

Zelda: Skyward Sword

Donkey Kong Country Returns

Definitely for 3DS:

Zelda: Ocarina of Time 3DS

Mario Kart 3DS

Paper Mario 3DS

Kid Icarus: Uprising 3DS

Most Likely for Wii

Kirby's Epic Yarn

Metroid: Other M

Most Likely for 3DS

Animal Crossing 3DS

Star Fox 64 3DS

Professor Layton and the Mask of Miracle 3DS

Most Likely for DS

Professor Layton and the Unwound Future

Okamiden

Somewhat Likely for Wii

Mario Sports Mix

Wii Party

Pokepark Wii: Pickachu's Adventure

Goldeneye 007

Somewhat Likely for 3DS

Hideo Kojima's Metal Gear Solid Snake Eater 3D "The Naked Sample" 3DS

Resident Evil: Revelations 3DS

Nintendogs and Cats 3DS

Somewhat Likely for DS

Super Scribblenauts

Mario vs. Donkey Kong: Mini-land Mayhem!

...Starting to rethink my decision not to get a job this summer....

Woh woh woh woh.  Woh.

There's a Paper Mario 3DS?  I know what just made the top of my list!

And that's just one screenshot.

Hopefully

Metroid, Zelda, Goldeneye, COD: Black Ops, Conduit 2, Donkey Kong, Epic Mickey, Kirby

I also will get a 3DS at some point, though maybe not right at launch

Halo Reach, Fable III, MoH, and CoD: Black Ops.

At this point, the only ones I can say for certain are;

Marvel vs Capcom 3, Donkey Kong Country Returns, LittleBigPlanet 2, The Legend of Zelda: Skyward Sword, Portal 2 and The Last Guardia- What? Oh that's right, it wasn't there!!