For the PS3, I'd have to give it to Uncharted for the moment. The environments are so lush and it looks gorgeous.
Mario Galaxy is a given for the Wii.
Halo 3 is sort of a given for the 360, too, unless Mass Effect becomes everything it's been hyped up to be.
Threads of Interest:
The Movie Thread: http://www.vgchartz.com/forum/thread.php?id=6880
The Crow Eating Thread: http://www.vgchartz.com/forum/thread.php?start=0&id=3886
The Betting Thread: http://www.vgchartz.com/forum/thread.php?start=0&id=7104
Custom GIFs Thread: http://www.vgchartz.com/forum/thread.php?id=18963
The Greatest Game Ever Conceived On Any Platform
Tag: "I have tasted Obi-Wan's bitter tears"