My PS3 have frose during playing Uncharted Drakes Fortune yesterday. This happens.

Probably just a random lockup.

I had about 10 from fallout 3 and my 60 gigger is still purring along nicely (the last time I checked it was anyway *touches wood*

not that wood, you pervert!

My PS3 froze on different instances, even while playing LBP. I just switch it off from the button and then usually turn it on there and then. Don't know if that is the wrong way to go.

Is Uncharted 2 pushing your PS3 hard? Probably.
Did your machine lock up while it was being pushed hard? I completely believe your account of what happened, so yes.
Did your machine lock up because there is a memory leak, bug, etc. in Uncharted 2 or a system library call that Uncharted 2 uses? Possibly.

Does your machine locking up while being pushed hard mean that the PS3 will be destroyed? It's theoretically possible, but unlikely. I know of about 3 instances over the past 30 years where software being developed by the team I was on actually fried hardware, and that was always due to some sort of glitch in the way the hardware was designed. It's just very rare for this scenario to exist.

So, while your machine locking up while it was being pushed hard seemed to indicate that the machine was being overstressed, this is not very probable... likely the two effects are separate and not related to each other. Welcome to the world of coincidence.

John is over 30.  John has brown hair.  All men over 30 have brown hair... BZZZTTT!  

Don't worry happened to me before nothing to be worried about.

I'd be more worried about the amount of time I lost on the game... there have been times where I've lost hours and hours of play... that's when I put the game up for a few months

don't worry. this happened to me twice already, i just turned it back on, no problems, i think its just the game making the ps3 work hard. LOL.

Dude, this happened heaps of times on my 40gb  when playing assassins creed of all games, a game that hardly pushes the PS3. I'd say the  double beep is just the PS3's way of saying that the Hyperviser (the Sony OS thats always operating in the background, behind the XMB) has had to reset the PS3 because something in the PS3 has stopped responding, which usually occurs with buggy code. My PS3 has never really spun up the fan much but it is both well ventilated and a PS3 Phat (although that includes Australian summer).

I'd just say its probably a software glitch in U2, and has nothing to do with any imminent death of your PS3. Start that sucker back up and get back into kicking arse U2.

i hear it happens alot on the older original ps3; i have the MSG 80g bundle and rarely get game lock ups during long sessions of play.

*Update*

Whew! Sparkie is fine.

I almost had a meltdown, I don't know what I would do if I didn't have teh cell in my life!