This recently happened to me...last week as a matter of fact. After about 15 hours of Bioshock playthrough, I took the console to my nephews where he started a new game. Neither one of us knew that when starting a new game under a profile that already has a game save, the autosave feature (on some games) will automatically overwrite your save file on autosave. Needless to say when it autosaved, it overwrote my save file leaving me mere minutes into the game. I was pissed, and usually I wouldn't pick the game back up for awhile, but quickly decided the best thing to do would be to just grin and bear it. The band plays on and now I am halfway back to where I was prior to the incident. Hopefully it shouldn't take as long to record the same progress.

"oh crap..."
I usually play it again, to the point where I lost the data so I don't have to go through next time.

every now and then b/c i will forget to save before getting into a tuff fight...then die....


but when i go to quite i always save twice just to be safe


but when i do have teh death loss..

first anger at myself then teh game..then resolution and i do it all over again and this time save

i will throw a anger fit and then cry especially if its been a wile since my last save and i will wait a long time before I will touch it again if ever just a few games its happened with Lost Odyssey, Resident Evil Remake, FFVII, tails of symphonia,
some others that were just OK games so I never played them again

Depends on the game. If the gameplay is simple fun (like say Puzzle Quest) I wouldn't care too much. But in linear story driven games or games based on advancement it can be a complete killer. I was playing a WWII shooter on DS (Brothers in Arms??) and it crashed and erased all my data. There was no way I was going to redo all those levels. I sold it.

I don't have a handheld, so it's not very often.... but on the very rare occasion I have had a disc read error it has annoyed me, but nothing more than that.

The most significant was for over 1 hour of play on LoZ:Windwaker, had it been my first playthrough I would probably have played on immediately, but it must have bee my 3rd time, and I lost pretty much all of the Tower of the Gods bit, and some siling on either side of it.... so I just left it for that day and picked it up from the previous save point in a day or two.

I've never turned off without saving, however sometimes I don't save for a while on a game and then die. When that happens I just stop playing the game and don't come back to it for a long while until it's not obvious that I'm just retracing my past steps.

When that happens, i take a few days off from that game then replay it. My silly mistake wouldnt prevent me from ever playing the game again, thats for sure

I don't have any idea of how many times I replayed a lot of levels from DKC, DKC2, Super Mario World, All-Stars and other SNES and even N64 games simply because I would lose whole saves, but today I wouldn't replay A LOT of them.

I usually save whenever I can so having to play again because of a missed save usually do not happen, and I can't even remember if it has ever happened.

but having to play again long parts because of game over usually keeps me from playing the game for quite some time

I cried..... Then flipped a quarter if I should sell the game or retry because if it goes up on the shelf it only comes out to play on days I have nothing... I mean nothing else to do.