This is a rumor by the way. Sorry I didn't mention that in the title.
http://kotaku.com/5010601/re5-to-have-2player-co+op-cover-system
A series first. According to a now pulled GamesRadar article, Resident Evil 5 will feature a cooperative player available throughout the campaign which lets players drop in and out of co-op play. The new cover system mechanics will let players "lock to a wall and fire around the corner." When not in co-op model, the other character will be AI controlled. What's more, the game will feature a dodging movement controlled by the right analog stick, and the game will take place in more open areas than previous RE titles.
Pretty interesting departure for the series if you ask me. 2 player co-op will add a lot of value to the game, and a cover system could be pretty interesting, although I don't think even RE4 needed one. It remains to be seen how necessary the cover system will be. My guess if there are more projectile/gun based enemies it will be important.
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