I have ot update my commentaries, I'll do it tomorrow or the day after :P

#39 - Look at the avatar.

Fire Emblem: Rekka no Ken

Mario Tennis

No

Hint #2:  They were the only new characters added to the series in this game.

Time to catch up!

Hint for #50:

This is a console remake of a 2004 PC shooter. The latest game in the series will be set in the Stone Age.

Far Cry Instincts

That's the one!

#50
Far Cry Instincts (Xbox, 2005)
guessed by CWegzz

On a system defined by its excellent first-person shooters, Far Cry Instincts stands out as one of the best. While less open-ended than the PC original, Instincts is a stellar game in its own right, boasting multiplayer modes, weapons, and "feral abilities" found only on Xbox. The environments in the game are gorgeous and detailed, and, despite the limited processing power of the Xbox, large enough to allow players to tackle objectives according to several different strategies. Want to go in guns blazing? No problem. Rather lure the enemy out and eliminate its forces one-by-one with deadly traps? Instincts has you covered. The result is a deep, surprisingly strategic shooter that ranks among the best Xbox has to offer.

Hint for #49:

The launch of this third game in the series was hurt by the release of N64, which arrived in North America two months earlier.