I really do not even believe this is a subject up for debate, but feel free:
Wii
1.) Super Mario Galaxy
2.) SSB:Brawl
3.) Metroid Prime:Corruption
4.) Resident Evil:UC
DS
1.) The Legend of Zelda:PH
2.) ASH
3.) Ninja Gaiden:Dragon Sword
4.) Dragon Quest Monsters:Joker
Worth mentioning & nearly making the DS list, Prof. Layton. Pre-rendered backdrops or not, ASH & Ninja Gaiden are beautiful to behold. (ASH's in-game character art esp.) Dragon Quest:IX would have made the list, but is being delayed until '08 afaik. As would the Wii's FFCC:Crystal Bearers, although the build we saw was still early in its development cycle.
edit: No More Heroes definitely deserves an honorable mention as well, somehow this title slipped my mind.
"The things we touch have no permanence."