I've been reading a lot of commentaries about the state of the industry, and I think this are the most endangered parts of the gaming industry.
-Mobile: It has grown too much and too fast. This kind of bussiness developement usually ends abruptly, and if we have into account the lack of loyalty and interest of the casual audience for this games, the terrible practises of mobile publishers, massive oversaturation and lack of quality control on the App store or Google Store, the day something cathes the eye of the mobile audience, the market will crash and burn anyone that invested too much on it. Specially worried with some japanese publishers, that have invested tons of effords and money on that market.
-Retail: The only thing that is stopping digital distribution into becoming the main form of distribution is the horrible pricing of most digital games on console. When publishers realize they can sell a lot of software (and hardware, PC hardware is usually more expensive, but you save in software, that logic can be applied in consoles too), the bigger chains of retail will have to reduce their size, and little stores will have to transform themselves into offering more veried services.
-Handheld: I don't think this will be a really big problem because, with the evolution of hardware, you can make wonders with portable devices. Even if now the only competitors on the market are Nintendo and Sony, we'll have handhelds in the future, even if they are combined or attached with their home consoles counterparts. With Sony becoming more interested in the mini-console market than in handhelds (their PS TV over the Vita lately), we'll have to see and wait what Nintendo does with the NX, whether it becomes a Fusion device or a regular handheld/home console. And even then, as long as Nintendo keeps Pokemon and some of their franchises on dedicated devices it will move a decent amount of consoles.
-Digital distribution on consoles: This is a weird theory of mine, but hear me out. If retail fails and digital becomes the prominent way of selling games, in a couple of decades we might see devices with no DVD-reader (or any kind of disk reader). After that happens, prices might start going up again because the console manufacturers have the monopoly on their distribution. That might anger gamers, because they can't use phisical copies anymore. In this case, consoles themselves might be in danger, but this situation is highly hypothetical, and it could only happen if the retail situation above happens.
What do you think will pop the videogame bubble first?