F-Zero's not, but Double Dash, Wind Waker, Sunshine, and Starfox Adventures are. :P
Even if you remove Mario (and since I don't care about Mario Kart, more the power for removing it too!), that still leaves F-Zero, Zelda (yep, even if I don't agree with that Wind Waker's notion, here comes Twilight Princess saving the day anyway!), Fire Emblem and Animal Crossing, not to mention Super Smash Bros Melee, which I forgot.
Gamecube's far from having the worst of Nintendo's series.