My nominations:
Retro City Rampage
Donkey Kong Country 3
Gears of War
Shadow of the Colossus
Mario Kart: Double Dash!!
The Elder Scrolls III
Panzer Dragoon
Super Smash Bros. Brawl
Devil May Cry (2001)
The Legend of Zelda
Halo 2
Demon's Souls
Tomb Raider II
Metroid: Zero Mission
Beyond Good & Evil
Super Mario Galaxy
The Legend of Zelda: The Wind Waker
Super Street Fighter II
Final Fantasy VII
Chrono Trigger
SoulCalibur
BioShock
Metal Gear Solid 3: Subsistence
Tetris DX
Psychonauts
Perfect Dark
Metal Gear Solid
Super Mario Galaxy 2
The Legend of Zelda: A Link Between Worlds
Ico
Metroid Prime
Super Mario World
Banjo-Kazooie
GoldenEye 007
The Legend of Zelda: Majora's Mask
Super Mario Bros. 3
StarCraft
The Legend of Zelda: A Link to the Past
Mario Kart 8
Super Metroid
Tomb Raider (1996)
Xenoblade Chronicles
Banjo-Tooie
Super Mario 64
Half-Life 2
Final Fantasy VI
Resident Evil 4
Halo: Combat Evolved
Deus Ex
The Legend of Zelda: Ocarina of Time