I don't think there will.
Microsoft only got close the once with Kinect Adventures on Xbox 360 with 24 million copies sold. I don't see a a Kinect game doing that again mainly because nobody really cares about the latest Kinect model, specially now Microsoft has made bundles without Kinect and now the Xbox 360 gets a 10% GPU increase without it.
Sony hasn't even managed to pass 20 million with an exclusive, even on PS2 so I doubt that. PS Vita is the least likely. I don't think the Vita has had any million seller titles yet or at least they haven't updated on their sales like they haven't with the sales on the handheld. NPD hasn't spoken about anything Vita for 1-2 years now.
Nintendo has had exclusives pass 30 million before, but sadly with how the Wii U is doing, they will struggle to make their exclusives pass 10 million. The only change we have is the Nintendo 3DS, but then even the DS only had one exclusive manage that so that isn't promising.
I
