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Er... the most profitable game on that list is Assassin's Creed, so I really don't see your point.

And RE5 and MGS4 will likely sell a lot more than any other game on that list... or any game on the Wii that isn't published by Nintendo.

Even Lost Planet (which was garbage) has sold reasonably well on the 360 alone, without even taking the PS3 and PC into consideration.