In order:
1. Gran Turismo 5 (assuming it makes it out in '09)
2. Killzone 2
3. God of War III (it will have a bigger opening than Killzone, but Killzone should have CoD4-ish legs, and Killzone will sell for the whole year)
4. Uncharted 2
5. InFamous
Heavy Rain will be niche, though it'll probably break a million due to Sony's marketing. It'll be Quantic Dream's best selling title, for sure.
As far as Japan is concerned:
1. Final Fantasy XIII (assuming it makes it out in '09)
2. Gran Turismo 5
3. White Knight Chronicles
Edit: Whoops, White Knight Chronicles is coming out in December in Japan.