Skyrim
LA Noire
Arkham Asylum
Assassin's Creed: Brotherhood
Telltale's The Walking Dead

in no particular order.

1. The Legend of Zelda: Twilight Princess
2. Uncharted 2 Among Thieves
3. Super Mario Galaxy
4. Guitar Hero III Legends of Rock
5. Uncharted 3 Drake’s Deception
6. BioShock (if #1 doesn’t count due to being cross-gen)

Xenoblade chronicles
Batman Arkham city
Mario Galaxy
Tomb Raider (reboot)
Zelda Skyward sword

Valkyria Chronicles
The Last of Us
Fallout 3
Mass Effect
Borderlands 2

In no particular order.

Mario Galaxy 2, Red Dead Redemption, Fire Emblem: Radiant Dawn, Castle Crashers, Skyrim, Call of Duty 4, Uncharted 2 and Left 4 Dead all narrowly miss out.

Not in any order:

Skyrim
Dragon Age:Origins
COD 4
Uncharted 3
Red Dead Redemption

Dark Souls 2
Fallout 3
Dead Space
Super Mario Galaxy
Punch-Out!!

Dark Souls
Valkyria Chronicles
The Last of Us
Ni No Kuni
Uncharted 2

Honourable mentions to Super Smash Bros. Brawl, Journey, Assassin's Creed II, Arkham City, Ratchet & Clank: A Crack in Time and Dark Souls II.

1. Atelier Escha & Logy: Alchemist of the Dusk Sky

2. Super Mario Galaxy 2

3. Kirby's Return to Dreamland

4. Tales of Vesperia

5. Tales of Xillia 2

1) The Last of Us
2) Grand Theft Auto V
3) Uncharted 2: Among Thieves
4) Assassin's Creed IV: Black Flag
5) Call of Duty: Modern Warfare

1 - Valkyria Chronicles
2 - Lost Odyssey
3 - Super Mario Galaxy
4 - The Legend of Zelda: Twilight Princess
5 - Resonance of Fate