Wii U Crystal Chronicles.
new Metroid
A new Pandemic-lead Star Wars Battlefront-esque game (sadly this one will never happen. Curse you EA)

Sega Rally 4, Dirt 4 (to be more rally oriented :)), Half Life 3 (wut), GTA Vita, Gran Turismo Vita, Unreal Tournament 4, Quake 5...

Red Dead

Demon Soul's 2

The Last Guardian... I know its announced but it may as well be unannounced at this point...

Also Half-Life 3

Fallout 4 - just like Fallout 3/NV in structure but with better visuals and less bugs. That would be heaven.

Valkyria Chronicles 4 - a proper one, either for PS4 or Vita.

Bloodrayne 3 - set in the world teased at the end, where vampires have taken over, or a prequel set in an earlier time period.

Borderlands 3 - I cannot wait for this one. Will be a blast.

Deux Ex - I enjoyed the last one quite a bit.

Torchlight - I want more.

Little Big Adventure 3 (let's see how many know this one =P)
Shadow of the Colossus 2 PS4, just thinking about it makes my head explode
Grandia IV
Metroid "5"
Red Dead 2
Naughty Dog and Santa Monica's new IPs
The Legend of Dragoon PS4 remake
Continue the Chrono series FOR GOD'S SAKE
Okami 2
Half-Minute Hero 2. There is one, but only in Japan. I'd like it on the Vita, it seems to suit the game more.

I'm pretty sure I'm forgetting something

A new Metroid game or a new F Zero game followed by a Doom 4 in the style of Doom 2, no more Doom 3 please.

Honest answer?

One that I actually expect to get: Fallout 4
One that I don't expect to get: Quest for Glory Reboot

Metroid 5