I've felt bad due to how my choices impact characters in game many times. Most recently in the Zero Escape series, every time I made a bad vote.
Oh damn ! I was just gonna talk about this one !
I'd say the worst moment ever I had in the game was to betray Luna during the vote, it never felt right and it never will. (I mean this specially once you see her ending)
Or to be honest, just pretty much about anybody in the game.(Except one) Although when I got thrown under the bus by others at last minute notice, I always felt an indescriptable sentiment of dread ...
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