I can't really say because spoiling anything from my top 50 list would be criminal, so I'll instead list some of the games I could have loved and wanted to play, but never got around to or was unable to:
hm... Persona 5 is definitely the one I most want to play. Nier: Automata, Cuphead look quite interesting too. Sonic Mania I can maybe consider because I didn't finish it, but I did play a good portion of the levels. I'm unsure about Horizon: Zero Dawn being a favorite but I'm sure I'd have enjoyed it. Crash N. Sane Trilogy would definitely be up there, but it is only a remake too... and then there's pretty much anything that released on Switch only of course. I don't have the system yet so there goes.