I can't wait for this, I've had it pre-ordered since July! As a huge fan of old school adventures (e.g. SCUMMVM is quite possibly the best open source application ever...) this looks like all kinds of awesome. As for future titles, I think Telltale has hired a Wii developer and will probably be watching Z&W pretty closely. Sam & Max or Bone would fit in well with the graphical stylings of other Wii games and would be instant purchases for me. :)
Anyway, I can't wait for the "Adventure Game" revival and the Wii looks like the perfect platform!