Most games on this list will hopefully launch before the end of 2009.
Exclusive Nintendo:
Kirby
Animal Crossing Wii
Disaster: Day of Crisis
Fatal Frame 4
Exclusive third party:
Sim City Creator
Star Wars: Clone Wars (Wii/DS exclusive?)
The Conduit (FPS)
Red Steel 2
Mad World
KORE
Fragile: Farewell Ruins of the Moon
Final Fantasy Crystal Chronicles: The Crystal Bearers
Monster Hunter 3
Rygar: The Battle of Argus
De Blob
Deadly Creatures
Lost in Blue: Shipwrecked
Mushroom Men
Sword of Legendia
Tales of Symphonia: Dawn of the New World
Call for Heroes: Pompolic Wars (only console exclusive)
Zombie Massacre
Sadness
Oboro Muramasa Yōtōden
The Sky Crawlers
Spyborgs
Multi platform:
Star Wars: The Force Unleashed
Alone In The Dark 5
Brothers In Arms: Road To Hill 30
Spider-Man: Web of Shadows
Ultimate Alliance 2
Medal of Honor: Vanguard
Call of Duty 5
Ghostbusters: The Video Game
Brave: A Warrior's Tale (Wii and PS2?)
Sonic Unleashed
Battle Rage: The Robot Wars
Lego Star Wars
Lego Batman
Rumored and stuff:
Prince Of Persia spinoff
Castlevania (might be Wii Ware and/or 2D)
C.O.R.E (Wii version off the DS FPS)
Target Terror 2 (for Wii?)
Shemue 1 and 2 gamapack
Games in the works without titles:
N-Space project
Factor 5 Wii Project (Kid Icarus?)
One more hardcore title hinted by IGN after Conduit?
There is a few titles on the way for the core/hardcore Wii player on the way. More will be announced, rumored or hinted by publishers/developers and gaming sites who holds information. Might not be as heavy titles as for Xbox 360/PS3, but it gets better almost every week. :)