Nina Struthers FTW

Nintendo, by far. Also interested in whatever is shown about FF7R in Square-Enix's conference.

I'm looking forward to more about the new Halo and the next Xbox so I'm going with Microsoft.

I just want to see Animal Crossing!

Well, this is probably the first year in a long time when I'm not really hyped for E3 because I have doubts any of these conferences would be really decent.

Bethesda - nothing interesting except Doom Eternal
Microsoft is already working on next gen, so I doubt they will have lots of new games shown this year unless they are really moving to that "beyond generations" strategy. If that neogaf leak is true, then this conference would be pretty boring IMO.
Nintendo - from the past few years, it doesn't seem that they take E3 really serious. Most of the interesting game announcements they do on their own directs throughout the year, so most likely E3 will be just a gameplay showcase for early announced games with a few new surprise announcements.
Square Enix - the only thing I'm interested to see from them is FFVII Remaster.
LRG - I always seem to skip their conference somehow. Probably they will show something interesting but I don't remember any big announcements from them for the past years.
PC Gaming Show - last year I fell asleep halfway through it. Don't see any big changes in this for this year.
Ubisoft, EA - not interested in these publishers games at all. But last year. Ubisoft at least had some funny moments so it was interesting to watch.

So, in conclusion, if I were to choose the one which is most anticipated, it would be either Devolver, because their conferences are the state of art or probably Microsoft for some big third party game announcements as Microsoft is the only conference this year where big third party games announcements can happen. But considering that most of developers are probably switched their focus to PS5/next-gen Xbox, I don't really see many announcements happening this year. So, I'll go with Devolver.

Of course I will try to watch every conference this year just like I did last year, but not setting my expectations high. Next year should be really big though.

Nintendo obviously. For all people want to claim about them not taking E3 'seriously'....well frankly they perform plenty well enough and don't have any reason to go in super deep into one game this year like in 2016 and 18.

I have to say I am most interested in Microsoft’s conference. This has been Microsoft’s worst generation by far. However, this conference is their chance to hit the reset button and start over. I want to see what their vision is for the next generation and I am hoping that they bring the games this time. The first two Xboxes were incredible consoles. I enjoyed both immensely with the 360 probably being my favorite console ever. Xbox one has been a giant disappointment. It has some ok games, but nothing great, and no features that really set it apart. This is Microsoft’s chance to get back in the game, and I am eager to see if they can do it. They are close to losing me as a customer, which is hard to do because I have always bought all the consoles.

Nintendo has one bad showing and people want to boycott their show lol. 2017 wasn't that long ago, and that conference was amazing.
I can't decide if I am more excited for Microsoft or Nintendo's conference.

As the old saying is go, people seek doom from Nintendo and get angry at the idea of not getting their doom. I'll admit that X-Box has the chance to make it hard for Nintendo to outdo them if they do a console blow out or make Halo the new Breath of the Wild, but we'll see in the end. 

I'm mostly interested in the Xbox show. I'm hoping to get food info about Xcloud and their next gen hardware offerings. It would be great to see some meaty Halo info as well, but I doubt were going to get much of that.