Many things would have to completely fall in line for me to quit gaming, thanfully they haven't completely all arrived or been lumped in at the same time. I do hate certain changes to the industry like DLC, changing the definitions of expansion packs and warping them from their original design, micro trans, macro trans, pre-ordering, content stripped and slapped into being DLC or pre-order "bonuses", store exclusive deals, basically anything that rips the game into tiny pieces and being sold at a higher price.
That and games being broken a lot more frequently on release or in the more recent case of MGSV, a game being sold incomplete but still willing to throw more money gouging obstacles in place.
I don't think I;d ever quit gaming entirely but I do know I;m not nearly as content and happy with gaming as I was at least 10 years ago or more, back then I hardly had much to worry about when buying a game, I simply bought it and was able to play the whole thing, now I have to do deep research into each and every game I might possibly want to buy and weigh in all the possible pros and cons from looking into it and then coming to a conclusion to which most of the time I;m usually let down for various reasons and that detracts me from gaming more in general, that and some of my favourite genres aren't what they used to be or are simply close to being dead like RTS. (C&C/AOE/Supreme Com style RTS before you jump the wagon and say it;s thriving because it's totally not).
Step right up come on in, feel the buzz in your veins, I'm like an chemical electrical right into your brain and I'm the one who killed the Radio, soon you'll all see
So pay up motherfuckers you belong to "V"