The most important casting for R&C was using the game's voice actors for Ratchet, Clank and Qwark. Good to the get Dr Nefarious VA on board too.
“The fundamental cause of the trouble is that in the modern world the stupid are cocksure while the intelligent are full of doubt.” - Bertrand Russell
"When the power of love overcomes the love of power, the world will know peace."
Jimi Hendrix