Well ultron has been defeated quite a bit over the years.
-Ultron-6 was tricked (by Pym) into self-destructing, destroying his entire body except for his head.
-Ultron-7 body wasn’t cast from Adamantium, making it somewhat easier to destroy. And, indeed, it was destroyed by the Fantastic Four a short time thereafter.
-Ultron-8 destroyed by the Scarlet Witch.
-Ultron-9 This one was knocked into a pool of liquid Adamantium which cooled, encasing him eternally in a block of the virtually indestructible ore.
-Ultron-10 destroyed by Machine Man.
-Ultron-11 Wonder Man tore Ultron-11 apart.
-Ultron-13 destroyed himself.
-Ultron-15 was destroyed by Pym using Antarctic Vibranium.
There is soooo many more. Ultron has been beat up quite a bit. The most important part of him is he's resilient. He finds a way to survive or he has a backup body. He's able to take control of people and robots, creating minions and bodies. Later on he finds a way to regenerate (heros of tomorrow) and he defeats a lot of people.