http://www.rotpod.net/rotpod/?p=1362
"Try to wrap your head around that for a second. Read that headline just a few more times to make sure that you aren’t confusing it with one of the ads on the side of the page of something. Got it? Good, because Kojima-san is not playing around when it comes to the file size of MGS4. In an interview with a Japanese mag, the Metal Gear Solid creator claimed that a 50GB Blu-ray is not sufficient for his upcoming title. Apparently, the team had to compress certain parts of the game to get it to fit on the Sony format, and foreign voice tracks were cut completely.
Kojima : I am not satisfied with the quality yet, however…there isn’t enough space.
Interviewer: Not enough space on Blu-ray?
Kojima: Yes. [laughter] Not enough space.
Someone get this man a Quad-Layer BD!"