Lifetime, almost for sure...
But even this year, is much probabily.
If the VGChartz number are correct, Destiny have sold less than 1.1m in USA. 200K in UK, and 100K in Japan. more than 2m globally?
In any case, i don't think that this year, Destiny will break 5,000,000... will sell good, but imho, Mario kart 8 will sell more than 5,000,000.
And if you think that is impossible because "have sold only 2.6 million now!"
New Super Mario Bros U have sold around 1.5 million on November+December 2013... Mario Kart 8 will sell of course more, so, with the September-October sales, that will be easy above 300,000-350,000, and with other 2,000,000-2,500,000 will sell above 5,000,000 by end of 2014.
So, Destiny for PS4 < Mario kart 8
This is only my opinion.