1.Pokemon Black And White
2.Super Mario Galaxy 2
3. Super smash bros Brawl
4.GTA 5
5.Civilization V
6.No More Heroes
7. Portal 2
8. inFamous
9.Minecraft
10.The Last story

Tough list to do. RDR is definitely my fave. Gears of War (original) would have made it for me since I find that game was awesome, but Max has a much bigger space in my gaming heart. Loved that game.

1 Read Dead Redemption
2 MGS4
3 Uncharted 2
4 TLOU
5 Mass Effect 2
6 Killzone 2
7 Uncharted 3
8 God of War: Ascension
9 Skyrim
10 Max Payne 3

1. Deus Ex: Human Revolution
2. Oblivion
3. Mass Effect 2
4. Skyrim
5. Dragon Age Origins
6. Mass Effect 3
7. Uncharted 2
8. GTA V
9. Portal 2
10. Bioshock Infinite

Edit- added next 5:

11. God of War III

12. Witcher 2

13. Fallout 3

14. Last of Us

15. Metal Gear Solid 4

Worth mentioning: Tomb Raider, Far Cry 3, Uncharted 3, Call of Duty 4

   1. God of War III
   2. Mass Effect 2
   3. Red Dead Redemption
   4. Bioshock
   5. The Last of Us
   6. Castlevania: Lords of Shadow
   7. Gears of War
   8. Alan Wake
   9. Deus Ex: Human Revolution
   10. Uncharted 2
   11. Tomb Raider
   12. LittleBigPlanet
   13. The Elder Scrolls IV: Oblivion
   14. Fable 2
   15. Dead Rising

Only chose 1 game per franchise for variety.

*edited

1. The Last of Us
2. Metal Gear Solid 4
3. Uncharted 2
4. Little Big Planet
5. Bioshock
6. God of War 3
7. Uncharted 3
8. Red Dead Redemption
9. Killzone 2
10. Battlefield: Bad Company 2
11. Batman: Arkham City
12. Call of Duty 4
13. Little Big Planet 2
14. Grand Theft Auto 5
15. Max Payne 3

Honourable Mentions:

Farcry 3
Bioshock Infinite
Burnout Paradise
Infamous
Gran Turismo 5
Journey
Mirror's Edge
L.A Noire

I added 10-15 (1 point each) so it gives people a little more room to vote.  i was having a hard time as well haha  But yeah you will have a long time to vote so take all the time you want :)  

Usually i try to keep these up by bumping for about a week to get as many people to vote as possible

#1: Metroid Prime 3: Corruption
#2: Phoenix Wright: Ace Attorney: Trials and Tribulations
#3: Super Smash Bros. Brawl
#4: Phoenix Wright: Ace Attorney
#5: Fallout: New Vegas
#6: Metal Gear Rising: Revengeance
#7: Minecraft
#8: Pikmin 3
#9: Bioshock
#10: Okamiden

If early Wii U titles don't count towards this gen, then #8 is Bioshock, #9 Okamiden, and #10: Asura's Wrath.

This is gonna be tough but here goes.....

1. Alan Wake
2. Mass Effect
3. Gears of War 2
4. Halo 3
5. Dragon Age: Origins
6. The Walking Dead
7. Dark Souls
8. Red Dead Redemption
9. Halo 4
10. Mass Effect 3

1. Persona 4 Golden  
2. GTA V
3. The Last of Us
4. Ratchet and Clank A Crack in Time
5. Bioshock Infinite
6. Tomb Raider
7. Ico and Shadow of the Colossus
8. Borderlands 2
9. Gravity Rush
10. Okami HD

Edit-Vita is next-gen Which makes GTA V number one and Okami number eight

Adding Tekken Tag 2 and God of War 3

1. Uncharted 2: Among Theives
2. Assassin's Creed II
3. Grand Theft Auto V
4. Mass Effect 2
5. Red Dead Redemption
6. The Last of Us
7. Gears of War 2
8. Lost Odyssey
9. Kingdom Hearts: Birth by Sleep
10. Total War: Shogun 2

11. Uncharted: Drake's Fortune
12. Crisis Core: Final Fantasy VII
13. inFamous
14. Mass Effect
15. Gears of War 3

Could also include Uncharted 3, Gears of War, Mass Effect 3, Deux Ex Human Revolution, XCOM, Halo Wars... I feel quite uncomfotable condensing about 8 years of gaming into 15 games, but Uncharted 2 is a very clear winner

I could probably go on editing the rest for weeks

EDIT: forgot CoD 4... a bit late, but it should definitely be on the list