I've gone in and out plenty of times, depending on what was happening in my life. Starting a new business, periods where I was hanging out pretty much every night, being really into reading for awhile, which was my first hobby, things like that.
Probably the most extensive absence, though, was after the SNES came out. I loved the NES but, other than a few games, like Zelda or FF VI, I didn't really care for a lot of what the SNES offered. There was a lot of duplication on that system, with pretty much everything I played being a variation of a platformer or a beat 'em up. FF VI was a revelation for me but I couldn't find anything else like it. I really became bored with gaming for quite awhile.
A few years later I started playing a few PC games but that was kind of a mild diversion. I only had a couple (though I spent many hours on Daggerfall). My PC was a mammoth Pac Bell that ran Mech Warrior at like 2 frames per second.
FF VI was one of the last console games I played, as I wasn't even into gaming when I spotted it on sale while with a friend, so it's kind of funny that FF VII is probably what brought me back. That commercial switched me from Nintendo to Sony and games like Final Fantasy Tactics, Gran Turismo, and Suikoden kept me from looking back. That's my the PS1 is my favorite all-time gaming system. It won me over in ways that none of my previous systems ever did, outside a few classics, and really got me more invested in gaming as a hobby rather than just something I did to kill time.