You mean a super mega massive mainstream hit? No, very unlikely. CoD4 blew the market away and has been riding the crest of a wave originally started by Halo. That wave will probably crash or divide out more evenly among top shooter titles rather than transferring over at this point. Online gaming has already reached prominence, there isn't much change for massive growth monopolization.
If PS4 is successful (which I think it will be) and Killzone launches showing off its capabilities, it could be synonymous with the system like Halo with Xbox. This could vault it into the 5 million territory, but not 13 million like COD nowadays (on one system).