Analysis from Bulbagarden from Neogaf (Bulbapedia, Pokemon Encyclopedia):
One more point in favour of why this is likely to be an announcement of mainline games....
The Pokémon anime in Japan has already reached the League, and that'll be over soon. We know they're going to follow that up with a story arc based around N (and presumably Team Plasma). While we don't know how long that arc will be, it would seem difficult to draw that out for too long. There's not really a lot left in B2W2 to develop into another story arc, besides maybe the World Tournament, and that's arguably already been done with the anime's "Junior World Cup" anyway. Barring the creation of an anime original region (which they've avoided since the end of Gen I), something totally unexpected (visiting regions from spin-off games like Colosseum), or the anime being brought to a close (highly unlikely), they're going to need a new game region to go to.
http://www.neogaf.com/forum/showpost.php?p=46057650&postcount=494
Read my original story on Fictionpress (Shinigami Twin): http://www.fictionpress.com/s/2996503/1/Shinigami-Twin
As well as my other one (Hell's Punishment): http://www.fictionpress.com/s/3085054/1/Hell-s-Punishment
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