According to the website it will cover Wii and 3DS news, so wont expect Wii U stuff.

What can we expect? 

3DS
New Super Mario Bros. 2
Taiko Drum
Culdcept
Animal Crossing
Etrian Odyssey IV
Rune Factory 4
Devil Summoner: Soul Hackers
Luigi's Mansion 2
Paper Mario: Sticker Star
New Training game

Wii
Fatal Frame 2 remake
Kirby Rom Collection
Dragon Quest X 

They will probably talk about Pokemon Black and White 2 and the Pokemon 3DS apps. I wont expect any news about Shin Megami Tensei IV because supposedly the first trailer will come with Soul Hackers, imo no Monster Hunter 4 either because of that CAPCOM event.

Website

Countdown

VicViper stole this from NeoGaf:

There's a WHAT!?

I'm flipping a table

How does something like this almost slip by us!?

What a wonderful surprise!

I like how Nintendo waits till the last sec. to announce their Nintendo Directs.

Hoping to see a lot of Japanese developed games for the Wii-U

Are they going to announce WiiUPad XL?
We need a 10'' screen to compete against tablets.

What time is this going on?

How hilarious would it be if they showcased a f zero, metroid title, and super smash brothers just to give E3 the middle finger? I know it won't happen but it would certainly be funny

Oh, crap, took me too long to make a thread :(

Anyway, great news!

3DS XL...

Let's all hold hands and sing together

Ya know whats great about the nintendo directs now? is the fact that they are done talking about the DS and Wii(well, except the pokemon B and W 2), so glad they've moved on. Can't wait to see what they have

8:00 PM US PDT

I updated the OP with a countdown and other stuff