So Naughty Dog recently said in an interview that the trailer is full of clues about the game so to keep watching over and over again. I've watched it a few times trying to find see any of these clues, and I think I found something (maybe).
Right at the end of the trailer there is the street scene with a highway sign over it:
So I zoomed in to see if I could get a better look at the sign and this is what it looks like:
After looking at it for a while and fussing around with google I think it says "Colerain Avenue" and US Highway 52 North. I think there is an interstate symbol in the upper left but I can't make it out.
After some more googling I found that Colerain Avenue pretty much always brings you to Cincinnati Ohio, which has a route 52 as well as other Interstates, take a look. Also on that map route 52 is also listed as interstate 74, which fits with the image because the interstate symbol looks like it only has two numbers.
What do you think? Naughty Dog has said in their minimal game description that they will go traveling across America, so this is probably only 1 location, but I think my detective work makes sense.
Platinums: Red Dead Redemption, Killzone 2, LittleBigPlanet, Terminator Salvation, Uncharted 1, inFamous Second Son, Rocket League
