Sazh from Final Fantasy XIII. The entire game had a really enjoyable cast IMO. Sazh however is one of the best in the entire series.

Lightning!

Runner up: Madison Page

Oswald the Lucky Rabbit (Epic Mickey)

Oswald hasn't been on the screen for a long, long time. In fact, it's been more than 80 years since the lucky rabbit has been seen. However, Epic Mickey put him back in the limelight that he so obviously adores (and we deserve!). His role in the game is fantastic, and leads the player to understand what it's like to be forgotten, and even then to lose everything. Still, even at the end of everything Oswald understands that Mickey doesn't have to be an enemy, but a brother. The ending is literally heartfelt as we see Oswald change from a jealous old scrooge to a lively and vibrant character, just like in those cartoons long ago.

Hopefully we wont have to wait another 80 years to see him on the screen again!

I liked Snow too! My second favorite of the FFXIII cast.

I'm thinking we will see him again next year.

In the PS3 version of Epic Mickey :p

Illusive man or Legion from mass effect 2.  

It's a tie between:

Cha-Cha from Monster Hunter Tri

&

Oichi from Sengoku Basara: Samurai Heroes

Lightning and Fang would have tied for my 2nd pick. :P

She was a smart strong woman, and even in her last moments she kept her calm and strenght.

Yeah boi!!!