I predict Halo reach will have best sales in 2010, while GT5 will have best lifetime sales. If nintendo decides to change Super Mario Galaxy 2, to Super Mario Galaxy Wii though, it will be well on its way to becoming the next 20mil+ seller and utterly crush both halo reach and GT5 sales combined.

My predictions

Halo Reach:

Week 1: 4.5mil

LTD: 11mil

GT5

Week 1: 2.2mil

LTD: 12mil

Super Mario Galaxy 2

Week 1: 1.8mil

LTD: 9mil

Halo Reach for sure, the new COD might be up high though like always.

honestly a game with strong, strong legs (nsmbwii)

maybe gt5

Out of these, Halo Reach.

I voted OTHER because a new COD will drop during the holidays again. We saw with MW2 what the COD franchise is capable of doing.

If were just talking sales for 2010 it will be halo reach. Anyone who thinks it will be anything else is delusional. However LTD sales it is anyones guess

Exclusives huh?...
Halo Reach will win by a few hairs.

Starcraft 2, assuming it drops this year.  Otherwise Halo Reach for sure.

LTD I believe will be GT5

this year, HALO REACH or galaxy 2 have a high chance, since those two games tend to have great openings more so than GT (based on past trends)

PC games have become far too pirated to have a chance to compete with console games in terms of sales anymore. Only suscription based games will have a chance. Sadly i doubt Starcraft 2 will sell close to what starcraft achieved, even if it does deserve it. I can't wait for it though personally.

Super Mario Galaxy 2 has a pretty good shot, if halo reach and GT5 don't live to expectations. Should have added newly released titles. OFC NSMBwii will win otherwise.